A REVIEW OF PSI

leprae. Anin silicostudy was performed to be familiar with the molecular interactions between DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 were being demonstrated to obtain larger inhibitory activity againstM. lepraeDNA gyrase than others. Also, Investigation making use of quinolone-resistantM. lepraeDNA gyrases confirmed that WQ-3334 had large